This does not mean that it is unsafe for children and young people to be prescribed such a medicine ‘off-licence/off-label’. Older medicines may have been used effectively for many years in children without problems but the manufacturer has not been required to collect data and amend the licence. In most cases, this is because the manufacturer will recruit adults to clinical trials in the first instance and therefore the initial marketing authorisation (licence) only covers adults and older children.įor new medicines, the manufacturer then has to recruit children and newborns into trials (unless the medicine is not going to be used in children and newborns) and subsequently amend the PIL with the approved information. 12 Nasal Units per 12 Days in 30 day period Maxalt (Rizatriptan Benzoate) 5mg and 10mg. For example, some manufacturers may recommend, in the patient information leaflet, that a medicine is not given to children aged under 12 years. Antimigraine Drugs Imitrex (Sumatriptan) 5mg and 20mg Nasal Spray. A few products do not have a marketing authorisation (licence) as a medicine and therefore there is no PIL.įor children in particular, there may be conflicts of information between the manufacturer’s patient information leaflet (PIL) and guidance provided by GOSH and other healthcare providers. If you do not have a copy of the manufacturer’s patient information leaflet please talk to your pharmacist. Please read this information sheet from GOSH alongside the patient information leaflet (PIL) provided by the manufacturer. Your doctor will explain this further to you. This is not necessarily hazardous but should be explained and agreed before use. Medicines are often used ‘off licence’ in children for a number of reasons for example limited data available for a specific use in children. Some types of triptan are not licensed for use in children. If one triptan does not work or causes side effects, your doctor will suggest another. Sumatriptan (available under the brand name Imigran®).Triptans do not prevent migraine or headache but they act on the pain once a migraine or headache has developed. There are several medicines in the triptan group including: They are also known as 5HT1-receptor agonists, which refer to the particular substance in the brain (5HT 1B/1D or serotonin) on which the medicines act. Triptans are a group of medicines used to treat migraine or headache. This page from Great Ormond Street Hospital explains about the medicines called triptans. Coming to GOSH for a day or inpatient admissionĬoming to GOSH for an outpatient appointment
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